Solutions
Recombinant Insulin
10 reasons why
Minimize contamination risks
Recombinant Insulin, also known as Insulin Human AF, is sourced directly from Novo Nordisk, a global leader in insulin production.
It is manufactured using a well-established, fully animal-free process involving microbial organisms. This minimizes the risk of contamination associated with animal-derived supplements and helps maintain consistency in cell culture media composition, reducing process variability.
Ensure consistent quality from batch to batch
With a focus on reducing process variability, our recombinant insulin is manufactured to the highest quality standards, ensuring consistently high purity across all batches.
This reliability translates into predictable and reliable performance when used in cell culture media for the production of various therapeutics.
Enhance mAb production
Studies have shown that the supplementation of Recombinant Insulin in the cell culture media of CHO cells leads to a substantial increase in monoclonal antibody (mAb) production.
This improvement is observed in both basal and feeding media, demonstrating the potential to enhance mAb production significantly.
Enhance cell-based vaccine production
The addition of Recombinant Insulin in chemically defined media has been shown to increase viral production in cell-based systems, such as in HEK293 and insect cells.
This supplementation resulted in a notable increase in Influenza virus production in HEK293 cells and an increase in viral particle production in insect cells.
Read more about the use of insulin for cell-based vaccine production here.
Increase viral vectors yield for gene therapy
Supplementation of insulin as an additive in chemically defined media has shown significant improvement for the growth of HEK293 cells and the production of various viral vectors for gene therapy.
This includes consistent increases in AAV and LV production, highlighting the potential for improving viral vectors’ yield for gene therapy applications.
Read more about the use of insulin for viral vector production here.
Improve stem cells performance
Incorporating insulin into cell culture media has shown benefits for fostering robust growth and sustaining induced pluripotent stem cells (iPSCs).
Optimizing insulin concentration in cell culture media is crucial for supporting proliferation while maintaining differentiation potential.
Read more about the use of insulin as supplement in iPSC culture here.
Ensure robust global supply chain
At Novo Nordisk Pharmatech A/S, we are committed to ensuring consistent availability and uninterrupted product supply through a robust risk mitigation strategy, manufacturing operations based in Denmark, and a secure supply chain with full traceability.
Simplify regulatory approval
Our product, manufactured through recombinant expression in yeast and free from animal-derived materials, adheres to stringent manufacturing standards and regulatory requirements.
This high-quality insulin expedites the regulatory approval process in biopharmaceutical production.
Partner with the preferred supplier
Our highly qualified personnel work continuously on product development and improving documentation to meet the ever-increasing global regulatory requirements, making Novo Nordisk Pharmatech a preferred supplier to leading biopharmaceutical companies worldwide.
Working with us is a valuable asset in minimizing risk as part of your risk management strategy.
Our expertise, combined with product and documentation availability and global compliance, ensures that partnering with Novo Nordisk Pharmatech provides a reliable and trusted source for your biopharmaceutical needs.
Meet high sustainability standards
Novo Nordisk Pharmatech is dedicated to operating at the highest standard of financial, environmental, and social responsibility, as evidenced by our top 1% company rating in the EcoVadis Sustainability Assessment Report.
This commitment simplifies compliance and provides independent validation of our practices, supporting sustainability goals.
Read more about our Ecovadis certification at our sustainability page here.
Want to learn more?
For more information about our Quats products, please contact us or visit our Quats product page.
Explore more about Recombinant Insulin
Insulin insights
Explore our collection of materials and case studies about Insulin Human AF and see how it improves cell culture and boosts protein production.
Recombinant Insulin
Scale-up production, optimise processes, and increase cellular products yields with our Recombinant Insulin that’s approved by regulatory bodies worldwide.
Insulin applications
Explore the many applications and learn how it can help support your formulations.
