Distribution of Benzalkonium Chloride into the aqueous phases of submicron dispersed systems: Emulsions, aqueous lecithin dispersion and nanospheres

Watrobska–Swietlikowska, D. Distribution of Benzalkonium Chloride into the aqueous phases of submicron dispersed systems: emulsions, aqueous lecithin dispersion and nanospheres. AAPS PharmSciTech Volume 21, 7 (2020). Abstract from the original article: Partitioning of benzalkonium chloride (BAC) into the aqueous phases of submicron dispersed systems such as submicron emulsions, aqueous lecithin dispersion (WLD), and suspension of nanospheres (NLC) […]

Ocular toxicity of Benzalkonium Chloride homologs compared with their mixtures

Akihiko Okahara et.al. Ocular Toxicity of Benzalkonium Chloride Homologs Compared with Their Mixtures. Journal of Toxicologic Pathology  Volume 26, 4 (2013). Abstract from the original article: This study was performed to assess the in vivo ocular toxicity of benzalkonium chloride (BAK) homologs compared with commercially available BAK (BAK mixture) and to assess the ocular toxicity of BAK […]

Local toxicity of Benzalkonium Chloride in ophthalmic solutions following repeated applications

Akihiko Okahara, Kouichi Kawazu. Local toxicity of benzalkonium chloride in ophthalmic solutions following repeated applications. Journal of Toxicologic Pathology Volume 38, 4 (2013). Abstract from the original article: We performed repeated toxicity studies of benzalkonium chloride (BAK)-containing vehicles of ophthalmic solutions in monkeys and rabbits to assess the local toxicity of BAK after repeated applications […]

Development and validation of a rapid ultra-high performance liquid chromatography method for the assay of Benzalkonium Chloride using a quality-by-design approach

Rangan M. et.al., Development and validation of a rapid ultra-high performance liquid chromatography method for the assay of benzalkonium chloride using a quality-by-design approach. Journal of Chromatography A, Volume 1413, September (2015). Abstract from the original article: A rapid robust reversed-phase UHPLC method has been developed for the analysis of total benzalkonium chloride in preserved drug formulation. […]

Analytical investigation of ternary mixture of phenylephrine hydrochloride, dimetindene maleate and benzalkonium chloride using validated stability indicating HPLC-DAD method

Abdelhamid A.G. et.al., Analytical investigation of ternary mixture of phenylephrine hydrochloride, dimetindene maleate and benzalkonium chloride using validated stability indicating HPLC-DAD method. Drug Development and Industrial Pharmacy, Volume 46,8 (2020). Abstract from the original article: A stability-indicating high performance liquid chromatography method with diode array detection (HPLC-DAD) was developed and validated for simultaneous determination of phenylephrine […]

Comparison of preservative-free and preservative-containing ipratropium bromide

Henry R.L. et.al., Comparison of preservative-free and preservative-containing ipratropium bromide. Journal of Paediatrics and Child Health Volume 25, 2 (1989). Abstract from the original article: A double-blind crossover study was performed on 33 children with asthma to compare the effectiveness of nebulized solutions of preservative-containing and preservative-free ipratropium bromide. Both solutions produced bronchodilation. No significant […]

Safety Data Sheets for BKC

Safety Data Sheets SDS for Benzalkonium Chloride Resources Our Safety Data Sheets (SDS) for Benzalkonium Chloride (BKC) are available for download below. These documents are prepared in compliance with the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as established by the United Nations (UN). Designed to help downstream users meet critical safety […]

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Topical formulations

Benzalkonium Chloride is a well-known antiseptic and has a long history of use in topical products such as antiseptic liquids, creams, and gels. It acts on a wide range of microorganisms including gram+ and gram-bacteria, mold, yeast, and enveloped viruses. Our Benzalkonium Chloride is colorless and odorless in finished product formulation, and its effectiveness in all […]