Effect of Insulin on influenza virus production in HEK293 Cells

Mammalian cells are considered an alternative to eggs for the production of influenza vaccines. HEK293SF-3F6 is a suspension GMP cell line that grows in serum-free media, and influenza production has been achieved in flasks and large bioreactors. To boost influenza production, insulin was added to the cultures. This growth factor was chosen because it has […]
The Insulin peptide family

Monoclonal antibodies | Viral vectors for gene therapy | Cell-based vaccinees | Pluripotent stem cells
The insulin and IGF-1 receptors

Monoclonal antibodies | Viral vectors for gene therapy | Cell-based vaccinees | Pluripotent stem cells
How insulin and IGF-1 bind to their receptors

Monoclonal antibodies | Viral vectors for gene therapy | Cell-based vaccinees | Pluripotent stem cells
Insulin and IGF-1 receptor signalling pathways: Where is the specificity?

Monoclonal antibodies | Viral vectors for gene therapy | Cell-based vaccinees | Pluripotent stem cells
A short history of cell culture media and the use of insulin

Monoclonal antibodies | Viral vectors for gene therapy | Cell-based vaccinees | Pluripotent stem cells
How cells grow, the discovery of Insulin like growth factors

Monoclonal antibodies | Viral vectors for gene therapy | Cell-based vaccinees | Pluripotent stem cells
Regulation of apoptosis by insulin and IGF-1

Monoclonal antibodies | Viral vectors for gene therapy | Cell-based vaccinees | Pluripotent stem cells
Regulation of the cell cycle by insulin and IGF1

Monoclonal antibodies | Viral vectors for gene therapy | Cell-based vaccinees | Pluripotent stem cells
Boosting influenza virus production in HEK293 cells with Recombinant Insulin

Cell-based vaccinees