Why cell-based vaccine developers should switch to TrypsiNNex®
Cell dissociation is just one step in your workflow, but it could be the one that determines whether a batch succeeds or fails. There is constant pressure in cell-based vaccine production to maintain consistency, prevent contamination, and meet strict regulatory demands – all under tight timelines.
That’s why high-purity reagents matter.
TrypsiNNex® sets a new standard for purity
Animal-derived trypsins contain an uncontrolled mix of isoforms, degradation products, and unrelated proteases – all of which contribute to inconsistent enzyme activity.
Recombinant TrypsiNNex® stands apart with ≥90% purity and well above 70% β-trypsin content – the active, stable form that delivers consistent performance. And because it’s entirely animal-free, it eliminates the risk of introducing adventitious contaminants into your upstream process.
This level of purity is more than just clean peaks. In cell-based vaccine development, it means:
- High cell viability: reduced surface damage and fewer unpredictable cleavage events
- Predictable, reproducible results: consistent enzymatic activity from a dominant β-trypsin profile
- Reduced batch-to-batch variability: uniform performance from every vial
- Animal-free formulation: eliminates contamination risks from animal-derived components
Built for the demands of regulated vaccine production
In high-stakes manufacturing, material quality can make or break your process. TrypsiNNex® is GMP-manufactured and backed by Novo Nordisk Pharmatech’s 75+ years of raw material manufacturing expertise. From documentation to delivery, it’s designed to meet the strict standards of regulated production environments:
- Comprehensive documentation: supports smooth regulatory submissions
- Secure supply chain: backed by a reliable, experienced supplier for the pharmaceutical industry
- Audit-ready quality systems: full cGMP compliance with a strong track record in global inspections
Still using a legacy trypsin? Uncertainty in enzyme composition could be holding your process back. Switch to consistency – TrypsiNNex® makes the smarter choice simple.
Where can I learn more?
More about TrypsiNNex®
TrypsiNNex®
Reduce resources needed for validation, improve process consistency and reduce costs due to contamination risk with our animal-free, recombinant TrypsiNNex®.
TrypsiNNex® applications
TrypsiNNex® specifically addresses the need for a consistent, high-purity and high-quality enzyme in biopharmaceutical manufacturing.
