Cell culture remains one of the most important bioprocessing tools we have today. The classic example of this process is the cell culture of a Chinese hamster ovary (CHO) cell line, used to express therapeutic proteins such as antibodies, cytokines, enzymes, and hormones.
Since 1980 insulin was found to be stimulatory in serum-free media for the growth of virtually every cell type examined. Today, the cell culture world is still divided into classical and serum-free solutions, but the industry is increasingly turning towards serum-free options.
The increased research and development around advanced therapies based on stem cells and chimeric antigen receptor T-cells (CAR-T cells) drives this movement, as these therapeutics require carefully balanced culture conditions and specialized cell culture media.
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